Ms. Edna Krabappel begins to lose faith in her relationship with Principal Skinner and becomes depressed. Bart wants to cheer her up and decides to nominate her for the Teacher of the Year Award. Ms. Krabappel and the Simpsons are given a free trip to Epcot Center in Orlando, Florida. Skinner decides that he needs to do something to win Edna back, so he follows them there. He tries to sabotage Edna's chances of winning the award, in hopes that she will become so depressed that she will come back to him. However, he has a change of heart and proposes to her.

Marge gets mugged and becomes so traumatized that she develops Agoraphobia. She hides in the basement. Having little else to do, she decides to exercise with a weight set Homer bought from Rainier Wolfcastle's garage sale. She becomes so strong and confident that she is able to leave the basement. She continues working out and decides to start taking steroids so she can enter a bodybuilding competition. One night at Moe's Tavern she loses her temper and starts destroying the bar and fighting all of the patrons. Homer confronts Marge and says he misses the sweet woman that he married. Marge, horrified at what she has done, apologizes and decides to stop working out.

Homer and Marge's bond becomes stronger when they both get drunk on wine, but soon the bond unravels when Homer blames Marge for crashing the car and Marge gets sent to rehab. Meanwhile, Bart and Lisa complain to Randall Curtis (a George Lucas-esque science fiction movie director) about his latest film.

When Grampa falls victim to a phone scammer, the Simpsons set out on a mission of vengeance to get his money back.